This course is jointly organised by Organised by the Institut Pasteur de Montevideo (Uruguay), the school of medicine of Montevideo (Uruguay) and the Emerging Disease Epidemiology unit from Institut Pasteur (Paris, France).

The course will be held at the Institut Pasteur de Montevideo (Uruguay), from Monday 9^th to Friday 21^st of April 2012 and will be provided in English.

Goals of the course

• Fecha: 29 de agosto a 2 de setiembre de 2011

• Horario: de 14 a 17 hs

• Lugar: Institut Pasteur de Montevideo

Metas del curso:
El curso consistirá en clases teóricas y talleres de discusión con la finalidad de familiarizar al estudiante con las técnicas de secuenciación masiva y sus aplicaciones en la genómica y biología molecular de hoy en día.

• Type: International Course
• Date: November 21st – December 2nd, 2011
• Place: Institut Pasteur de Montevideo

The aim of the course is to offer training opportunities to PhD students and Post-docs in Functional Genomics, a rapidly envolving area of biomedicine and biotechnology with high impact in the diagnosis, prognosis and treatment of human and animal disease. The first edition of this course two years ago was mainly focused on microarray technologies. Today, the advent of next-generation sequencing technologies (NGS), and the application of new mutational screening strategies are taking genome studies to new dimensions. Therefore, in this updated second edition, the focus will be put not only on basic microarray technologies but it will also include the latest knowledge on NGS and genome-wide RNAi high-throughput screening techniques.

• Course: Redox Chemistry and Biology of Thiols
• Type: International course
• Date: March 21st - April 1st, 2011
• Place: Institut Pasteur de Montevideo
• URL: http://www.pasteur.edu.uy/rcbt

The course will consist of four main activities: theoretical lectures, experimental training, seminars and a research symposium. The theoretical lectures will address the most relevant concepts and topics related to redox biology and chemistry of thiols and will be presented by scientists that are internationally recognized as experts in their fields. The lectures will be accompanied by seminars, where the students will have the opportunity to present and discuss original scientific articles of recent publication. In most cases, articles will be selected among the production of the teachers of this course, so as to allow the students to discuss them directly with the authors. The experimental activities will cover different methodological approaches and techniques to characterize the (bio)chemical properties of thiol groups and their physiological (or biological) relevance.

• Course: Yeast Systems Biology
• Type: International Course
• Date: November 7th - 22nd, 2011
• Place: Institut Pasteur de Montevideo

The global aim of this course is to equip students to address biological questions from a comprehensive and quantitative perspective.

• Couse: Coarse-Grained Biomolecular Simulations
• Type: International course
• Date: October 2011
• Place: Institut Pasteur de Montevideo
• URL: http://www.pasteur.edu.uy/cgbs

The recent development of simplified or coarse grain (CG) representation of molecular systems added to growth of computational power allow nowadays the study of size and timescales that really match those biologically and technologically relevant.

• Course: Functional Genomics in Biomedicine
• Type: Internatioinal course
• Date: November 21st - December 2nd, 2011
• Place: Institut Pasteur de Montevideo

• Course: Macromolecular Crystallography: introduction and applications.
• Type: International workshop
• Date: 26th April – May 7th, 2010
• Place: Institut Pasteur Montevideo

X ray crystallography is one of the most powerful methods to determine the three-dimensional structure of biological macromolecules with atomic resolution. The principal aim of this course is to give intense hands-on training in all main aspects of macromolecular 3D structure determination by X ray diffraction.

• Course: Mass Spectrometry in Protein Analysis and Characterization
• Type: EMBO World Practical Course
• Date: March 16th – 26th 2010
• Place: Institut Pasteur de Montevideo

Intended (but not restricted) to PhD students and post-PhD fellows, young people involved in teaching and research at Universities or at public research institutes.