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Macromolecular Crystallography: introduction and applications

poster

International workshop
April 26th – May 7th, 2010
Institut Pasteur Montevideo
Montevideo, Uruguay

X ray crystallography is one of the most powerful methods to determine the three-dimensional structure of biological macromolecules with atomic resolution. The principal aim of this course is to give intense hands-on training in all main aspects of macromolecular 3D structure determination by X ray diffraction.

The course will include lectures delivered by a number of international experts in the discipline, linked to hands-on experimental work and software tutorials. 

 

It is intended for advanced graduate students, postdocs and young investigators who deal with structural biology or are willing to get involved.

Official language will be English.

 

Organizers

  • Alejandro Buschiazzo, PhD (Unit of Protein Crystallography, Dept. of Structural Biology, IP Montevideo, Uruguay)
  • Pedro Alzari, PhD (Unité de Biochimie Structurale, IP-Paris, Francia)
  • William Shepard, PhD (Synchrotron SOLEIL, L'Orme des Merisiers Saint-Aubin, Francia)

 

Program

The course will have strong theoretical lectures as well as intense hands-on practical work. The emphasis will be on:

  • setting up experiments with the installed, state-of-the-art crystallization and diffraction instrumentation available at the Pasteur Institute of Montevideo (macromolecular crystallogenesis, robotics-assisted screening strategies; cryocrystallography; single crystal X ray diffraction data collection);
  • processing and analyzing the diffraction data; and,
  • analyzing the derived atomic models and structural data (critical reading of Structural Biology scientific reports).

For a detailed program and scheduled activities, click here. This program will be adjusted: please check for future updates.

In order to achieve the workshop's goals, established, state-of-the-art experimental techniques and software will be employed. A prestigious staff of invited speakers, from the region and abroad, will guarantee an excellent level.

Confirmed invited lecturers.

 

How to apply

Applications should include:

  • Short CV (age, current position, scientific interests, publications)
  • Reference letter from direct supervisor
  • Letter of motivation : special emphasis should be given at how Protein Crystallography will be important in the student's ongoing research project(s).

Inscription fees are fully covered for all accepted students. Applicants from abroad with no financial support, are welcome to apply for a lodging and per diem expenses scholarship. This should be inlcuded as a separate document at the time of application. A limited number of traveling aids will be available: arguments backing this request should be duly explained, to be evaluated on a case by case basis.

Applications must be sent in .PDF files to: crystallography@pasteur.edu.uy, before March 7, 2010

Deadline for applications: March 7, 2010

Supported by:  Reseau International des Instituts Pasteur (RIIP), Programa AMSUD/Pasteur, Institut Pasteur de Montevideo (URUGUAY INNOVA), Centro de Biología Estructural del Mercosur (CeBEM)